WebBuforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive … WebFeb 1, 2024 · In contrast to membrane active peptides, the antimicrobial peptide buforin2 acts on intracellular targets, probably DNA and RNA. The peptide translocates into the cell and binds to DNA, leading to death of the bacteria [17]. AMPs are found throughout nature, including in microorganisms, plants, insects, and mammals. Many AMPs have been …
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The membrane action mechanism of analogs of the
WebDec 24, 2024 · The emergence of drug-resistant bacteria emphasizes the urgent need for novel antibiotics. The antimicrobial peptide TS shows extensive antibacterial activity in vitro and in vivo, especially in gram-negative bacteria; however, its antibacterial mechanism is unclear. Here, we find that TS without hemolytic activity disrupts the integrity of the outer … http://www.inhibitor-expert.com/objective-the-aim-of-this-study-was-to-investigate-the-suppressive/ WebFeb 28, 2024 · Here, we conjugated the antimicrobial CPP buforin II (BUF2) to the surface of magnetite nanoparticles to enhance their cell penetration. Conjugates were characterized via Fourier transform infrared spectroscopy, dynamic light scattering, and thermogravimetric analysis, and their biocompatibility was corroborated. 16mw海上风电机组