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Early endosome antigen 1

WebMar 8, 2024 · d LgBiT-FYVE and Early Endosome Antigen 1. In both cases, secondary antibodies coupled with oligonucleotides (PLA probes) bind to the primary antibodies. When the PLA probes are in close proximity ... WebEarly Endosome Antigen 1. In the case of the EEA1 FYVE domain, the emission of a single conserved tryptophan residue located in the head group binding site is quenched …

EEA1, an early endosome-associated protein. EEA1 is a

WebNov 29, 2016 · Early endosome antigen-1 and Ras-related protein-11 expressions were upregulated; however, the localized distributions of these pivotal proteins were altered. We hypothesized that these LVLS were held by the internalized and dispersed particles decreasing the amount of cell membrane available to support the completion of cytokinesis. WebSep 17, 2024 · The crucial effectors of Rab5 are early endosome antigen-1 (EEA1) [28, 29], rabaptin-5 [30, 31, 37], rabenosyn-5 [32, 38], APPL1/2 [33, 34], and ZFYVE21 (Table 1). EEA1, a key effector of Rab5 with a molecular weight of 162 kD, is a biomarker for early endosomes and has a parallel coiled-coil homodimer structure. bio market insights https://bel-bet.com

Endosomal Marker Antibodies Thermo Fisher Scientific

WebDec 14, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains … WebJul 10, 2024 · At this stage, ingested materials can be recycled back to the plasma membrane, sent to the trans-Golgi Network (TGN), or degraded through endosomal acidification. Each compartment in the pathway is marked by characteristic proteins, such as early endosome antigen 1 (EEA1), lysosomal-associated membrane protein 1 … WebJan 3, 2024 · EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast … biomark research影响因子

The FYVE Domain of Early Endosome Antigen 1 Is …

Category:Eea1 MGI Mouse Gene Detail - MGI:2442192 - early endosome antigen 1

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Early endosome antigen 1

Anti-EEA1 Antibodies Invitrogen - Thermo Fisher Scientific

WebJun 2, 1995 · Early endosomes are cellular compartments receiving endocytosed material and sorting them for vesicular transport to late endosomes and lysosomes or for … WebEarly endosome antigen 1 (EEA1) is 170-kDa polypeptide required for endosome fusion. EEA1 binds to both phosphtidylinositol 3-phosphate (PtdIns3P) and to Rab5-GTP in …

Early endosome antigen 1

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WebThank you for your interest in NeuroMab™ anti-Human Early Endosome Antigen 1 (EEA1) IgG fraction Antibody. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n): WebEarly Endosome Antigen 1 Studies of EEA1 have been instrumental in defining the localization of PI(3)P. Closer examination of the protein reveals it is a large coiled-coil protein (Figure 138.3a) that can bind to the GTP-bound form of Rab5, a GTPase required for endosomal membrane fusion [17].

WebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in segments centered around amino acids 515 and 645. EEA1 contains an N-terminal zinc finger motif, a cys-rich C-terminal metal-binding finger, and multiple sites for N … WebEarly endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like ...

WebFeb 1, 2004 · Rab5 together with early endosome antigen 1 (EEA1) 118,119,120 — a phosphoinositide-binding protein — regulate fusion between primary endocytic vesicles and sorting endosomes. More … WebEarly endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations.

WebEEA1 early endosome antigen 1 [ (human)] Gene ID: 8411, updated on 8-Jan-2024 Summary Enables 1-phosphatidylinositol binding activity; GTP-dependent protein binding …

WebMar 3, 2015 · To investigate whether GALNT1 regulates EGFR trafficking, immunofluorescence staining of GALNT1 knockdown HA22T and PLC5 cells treated with EGF 10 ng/ml was performed to analyze for co-localization of EGFR (red) with early endosome antigen 1 (EEA1) (green) or lysosomal associated membrane protein 1 … biomark softwareWebSep 27, 2016 · Sequence analysis predicted that the 1,411-amino acid EEA1 protein is largely hydrophilic with short amphiphilic regions in the 15 N-terminal amino acids and in … biomark handheld readersWebThe FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization. Lawe DC, Patki V, Heller-Harrison … daily poker tournaments in biloxiWebThe endocytic vesicles mature to early endosomes and then the late endosomes by inward budding of the plasma membrane. The late endosomes turn into MVBs by accumulating the intraluminal vesicles ... Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. Eur J Immunol 2003; … biomark healthWebEarly Endosome Antigen 1 Studies of EEA1 have been instrumental in defining the localization of PI(3)P. Closer examination of the protein reveals it is a large coiled-coil … biomark research ucWebNov 28, 2024 · c Statins counter Mycobacterium tuberculosis-induced phagosome arrest by inducing the expression of early endosome antigen 1 (EEA1), which might be due to increased Ca 2+ levels in macrophages. biomark production departmentWebApr 27, 2024 · Therefore, we, co-transfected cells with the well-known tethering protein early endosome antigen 1 (EEA1) tagged to GFP (EEA1-GFP) (Bergeland et al., 2008; … biomark oncology