Web12 apr. 2024 · Esketamine is a pure dextro-enantiomer of ketamine and an NMDA antagonist with potent analgesic and bronchodilator effects. In this study, Dixon sequential method was used to study the median effective dose ( ED50 ) of intravenous esketamine pretreatment to prevent sufentanil-induced cough, and to explore the effect of age on … WebAdequate studies to evaluate the impact of ketamine on male or female fertility have not been conducted. Male and female rats were treated with 10 mg/kg ketamine IV (0.8 times the average human induction dose of 2 mg/kg IV based on body surface area) on Days 11, 10, and 9 prior to mating. No impact on
Ketamine: Use in Anesthesia - Wiley Online Library
WebEffect of ketamine and SD on EEG sleep power spectrum during the early recovery period. The 6 h of SD resulted in an increase in sleep and similar results were obtained after the initial 2-h waking period (CT1-CT3) induced by the ketamine administration. Web1 okt. 2024 · Ketamine doses of 0.04 to 2.5 mg/kg/h (0.7-41.7 µg/kg/min) for a median duration of 2.8 days resulted in lower sedative and analgesic doses after the initiation of ketamine. 22 These findings support the theory that ketamine can be safely used as an adjunctive agent for sedation and analgesia in patients receiving mechanical ventilation. … goif off
Ketamine - an overview ScienceDirect Topics
Web6 apr. 2024 · Co-administration of inactive doses of molsidomine (1 mg/kg) and clozapine (0.1 mg/kg) counteracted delay-dependent and ketamine-induced non-spatial recognition memory deficits. The current findings suggest that molsidomine is sensitive to glutamate hypofunction since it attenuated behavioral impairments in animal models mimicking the … WebAn induction dose of ketamine 1–2 mg/kg IV induces dissocia-tive anesthesia 1–2 min after IV injection. This is longer than the arm-brain circulation time desired for “rapid” unconsciousness. In a critically ill patient, ketamine provides cardiovascular stability, because it exerts sympathomimetic action in patients with an Web26 apr. 2024 · The original DSI study demonstrated the technique for use in preoxygenation or for pre-intubation nasogastric tube placement in upper gastrointestinal hemorrhage.9DSI starts with dissociative-dose ketamine: 1–2 milligrams per kilogram (mg/kg) intravenously (IV) or 4–6 mg/kg intramuscularly. goif programs facebook