WebbAt the beginning of 2010, the patient was admitted to inhaled rGM-CSF (Sargramostim) therapy as compassionate treatment. GM-CSF was administered by Akita 2 nebulizer … WebbBackground and Importance Autoimmune pulmonary alveolar proteinosis (aPAP) is a disease caused by IgG antibodies against granulocyte-macrophage colony-stimulating …
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Webb29 maj 2024 · Savara's pipeline comprises: Molgradex, an inhaled granulocyte-macrophage colony-stimulating factor, or GM-CSF, in Phase 3 development for … Webb1 sep. 1999 · Abstract. The objective was to study the feasibility of granulocyte macrophage-colony stimulating factor (GM-CSF) delivery to the lung using an aerosol … kristen crawford md madison ms
Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies
Webb7 okt. 2024 · Early treatment with inhaled GM-CSF improves oxygenation and anti-viral immunity in COVID-19 induced lung injury – a randomized clinical trial October 2024 … Webb6 feb. 2014 · Biopsy-proven PAP was identified in 10 adults (18%), all of whom lacked anti-GM-CSF autoantibodies and whose disease was refractory to subcutaneous and inhaled GM-CSF therapy (Figure 3G-H). Five patients with PAP (9%) went on to have subsequent pulmonary arterial hypertension (PAH). Webb15 dec. 2024 · GM-CSF neutralizing autoantibodies in pulmonary alveolar proteinosis (PAP) have led to a lack of phagocytic function of alveolar macrophages. 37 … map of 89119