WebMar 20, 2014 · About a quarter of patients with severe aplastic anemia remain pancytopenic despite immunosuppressive therapy. We have previously demonstrated that eltrombopag has efficacy in this setting with 44% (11/25) of patients having clinically significant hematologic responses. WebMar 9, 2024 · All patients were refractory to a high dose of corticosteroids (at least 1 mg/kg day) and prior immunosuppressive treatment with thrombocytopenia, including cyclosporine A (86.7%, 13/15), IVIG...
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WebApr 20, 2024 · In patients with aplastic anemia that was refractory to immunosuppression, eltrombopag, a synthetic thrombopoietin-receptor agonist, led to clinically significant increases in blood counts in... WebJun 6, 2024 · Introduction. Immune-mediated destruction of hematopoietic stem and progenitor cells (HSPCs) is the principal mechanism responsible for severe aplastic … kitchen tall bookcase
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WebAplastic anaemia (AA) is a rare disorder in children. This amendment covers children up to the age of 16 years. The work-up and supportive care of aplastic anaemia in children should be as per the adult guidelines (Killick et al, 2016). WebApr 4, 2024 · Rates of graft-versus-host-disease-free survival in treatment-naïve and refractory disease compare very favorably to standard therapies. Abstract Severe aplastic anemia (SAA) is a stem cell disorder often treated with bone marrow transplantation (BMT) to reconstitute hematopoiesis. WebAllografting in patients with severe, refractory aplastic anemia using peripheral blood stem cells and a fludarabine-based conditioning regimen: The Mexican experience kitchen tall cabinet storage