WebbBoth in algae and in plants riboswitch deficiency altered thiamin metabolism (see above). Although no negative effect on the growth of the Chlamydomonas mutant (i.e. pyr1) was observed (Moulin et al., 2013), Arabidopsis plants harboring the deficient TPP riboswitch displayed a strong physiological and metabolic phenotype (Bocobza et al., 2013). Webb全聘课题组长. 首页 人才队伍 全聘课题组长. 顾宏周. 博士,研究员,博士生导师. 地址: 东安路130号,西13楼421室,上海 200032. 电话: 021-54237322. 邮件: [email protected].
Analysis of Chlamydomonas thiamin metabolism in vivo reveals …
WebbThiamine metabolism genes are regulated in numerous bacteria by a riboswitch class that binds the coenzyme thiamine pyrophosphate (TPP). We demonstrate that the … Webbthiamin riboswitches from analyses in vitro of TPP binding to the reconstituted aptamer domain (9–13). However, the requirement for these RNA sensors and their specific … can i pour bleach in my pool
Regulation of the thiamine pyrophosphate (TPP)‐sensing …
WebbSamuel E. Bocobza, Sergey Malitsky, Wagner L. Araújo, Adriano Nunes-Nesi, Sagit Meir, Michal Shapira, Alisdair R. Fernie, Asaph Aharoni, Orchestration of Thiamin Biosynthesis and Central Metabolism by Combined Action of the Thiamin Pyrophosphate Riboswitch and the Circadian Clock in Arabidopsis, The Plant Cell, Vol. 25, No. 1 (JANUARY 2013), … WebbObjectives The development of novel antibiotic compounds requires riboswitches; in fact, riboswitches are RNA elements present in the 5′ untranslated region of bacterial mRNA and have a metabolite-binding aptamer domain and an expression platform regulating the expression of vital genes. In the present research, one riboswitch, namely thi-box … WebbThe thiamine riboswitch is a post-transcriptional mechanism for TPP to repress gene expression and it is located on A. nidulans thiA pre-messenger RNA. The thiA riboswitch was not fully derepressed under thiamine-limited conditions, and fully dere-pressed under environmental stressors. Upon expo-sure to hypoxic stress, the fungus accumulated more can i pour ammonia down my drain